• Clinicians brainstorming solutions
  • Clinician using Keriton application
  • Clinicians reviewing Heart Safe Motherhood dashboard
  • Patient receiving care at home

We reimagine health care delivery for dramatically better outcomes.

Learn about the Center for Health Care Transformation and Innovation
Nudge Unit logo Designing and implementing scalable nudges to improve medical decision-making and patient outcomes Learn more Way to Health logo Providing technology infrastructure for sustainable behavior change interventions Learn more PHL logo knockout Rapidly evaluating and implementing evidence-based interventions to improve health outcomes at scale Learn more Center for Health Justice text logo Enabling health through racial, economic, and environmental justice Learn more

Impact

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$106M
in grants and awards
75+
solutions implemented
560+
publications

Featured News

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Nudges help more ED patients access treatment for alcohol misuse Annals of Emergency Medicine A Penn Medicine Nudge Unit initiative increased naltrexone prescribing for patients with alcohol-related conditions – from 0.2 percent up to 3 percent – in emergency departments (EDs), helping more patients access evidence-based treatment before leaving the hospital. The intervention uses behavioral science and EHR-based nudges to make it easier for clinicians to identify eligible patients, prescribe medication, and connect them with additional support. The work has drawn national attention, including coverage in STAT News, as a promising approach to addressing the growing impact of alcohol misuse. Read more
Automated calls reduce missed appointments NEJM Catalyst A CHTI-led trial found that automated phone calls help reduce the no-show rate among patients most likely to miss their appointments. When these patients received calls that let them easily confirm, cancel, or reschedule, the no-show rate dropped by 1.7 percentage points. The approach proved effective over time and has since been expanded across the health system using a scalable communication platform. Read more
Learning how to make change: Reflections from Transformation Fellow Therese Murphy Therese Murphy reflects on her first year as a CHTI transformation fellow working on the OnePenn Breast Oncology initiative—where progress came through steady, behind-the-scenes work. The experience reshaped how she sees systems and change, and confirmed that transformation work is measurable, meaningful, and worth building a career around. Read more
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